Schizophrenia may develop due to genetic mutations
The reason for the development of schizophrenia can be a different gene mutations that destroy biological ways, it is vitally necessary for normal brain development. This conclusion came scientists from the University of Washington in Seattle and specialists Cold Spring Harbor Laboratory in New York, said agency Reuters.
Schizophrenia - is a complex mental disorder characterized by delusion, hallucinations and sputannym consciousness. Suffered from schizophrenia for about 1% of the adult population. For a long time, the experts were trying to establish the causes of the disease and to determine the role of genetics and environmental factors. The opening made by scientists in the latest study confirmed the theory that schizophrenia responsible for one or more key genes, and the many and varied setbacks in a large number of genes.
As it turned out, and damage to DNA duplication, destructive genes, often from schizophrenic. From these damaged genes depend biological ways that play an important role in the development of the brain - they are involved in building infrastructure, in which the interaction of neurons and growth, migration and cell necrosis.
The work by researchers from the University of Washington and Cold Spring Harbor Laboratory studied the DNA of 150 schizophrenic and 268 healthy people. Analysis showed that the destruction of DNA duplication, and is available to 15% of patients with schizophrenia and only 5% of healthy participants in the experiment. Similar results obtained specialists and the National Institutes of Health in the United States studying the DNA of patients who became ill schizophrenia in childhood - genetic faults were found in 20% of subjects.
The authors of the study suggest that the results of their work to develop new medicines and treatments of schizophrenia based on biological ways to stabilize the devastated genetic anomalies.